Lifestyle

Elucidation of antiviral/innate immune response activation mechanism of hepatokine LECT2

Innate immunity is activated when the pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs). A research team from Kanazawa University has shown that a liver-derived secretory protein LECT2, a hepatokine, binds to the HGF receptor MET, a proto-oncogene product, to suppress the proliferation signal of MET. LECT2 activates retinoic acid-inducible gene-I, enhancing antiviral and […]

Lifestyle

Researchers discover neuronal cell type for controlling the flow of information in the brain

A scientific team from MedUni Vienna’s Center for Brain Research has now identified specific cells that regulate the transmission of information between brain areas. This discovery forms the basis for the development of new treatment options for neuropsychiatric disorders such as schizophrenia and autism, which are characterized by impaired coordination of information flow in the […]

Lifestyle

Comparing physicians’ performance to peers decreases job satisfaction and increases burnout

A commonly used behavioral intervention—informing primary care physicians about how their performance compares to that of their peers—has no statistically significant impact on preventive care performance. It does, however, decrease physicians’ job satisfaction while increasing burnout. Burnout rates among physicians are rising—often resulting in mental health problems, job turnover, and higher healthcare costs. Meanwhile, health […]

Lifestyle

Seizures may increase dementia risk for young stroke survivors

Young stroke patients who have a seizure following their diagnosis are two and a half times more likely to develop dementia than patients who don’t experience seizures, according to a new study by Penn State College of Medicine researchers. They said their results warrant further study into whether monitoring and treating young stroke survivors —those […]

Lifestyle

Your medical hurricane prep checklist

While a hurricane preparation checklist for anyone in a hurricane zone should cover basic needs for several days, those with health conditions may need additional items and should keep certain considerations in mind when deciding whether to evacuate. Dr. James McDeavitt, executive vice president and dean of clinical affairs at Baylor College of Medicine, explains. […]

Lifestyle

Y chromosome loss through aging can lead to an increased risk of heart failure and death from cardiovascular disease

The Y chromosome can be lost through the process of aging, and this can lead to an increased risk of heart failure and cardiovascular disease, according to a recent study my colleagues and I published in the journal Science. While most women have two X chromosomes, most men have one X and one Y. And […]

Lifestyle

Nonopioid pain prescriptions increased after 2016 CDC guideline, study finds

After the Centers for Disease Control and Prevention released a guideline for prescribing opioids to patients experiencing chronic pain in 2016, the prescribing rate of non-opioid pain medication increased each year above and beyond what would be expected based on the preexisting trends, a new study finds. The 2016 guideline aimed to help U.S. clinicians […]